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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GRM3 All Species: 20.3
Human Site: S381 Identified Species: 37.22
UniProt: Q14832 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14832 NP_000831.2 879 98879 S381 D K H L A I D S S N Y E Q E S
Chimpanzee Pan troglodytes A3QNZ8 839 95029 S372 N C L N A T L S F N T I L R L
Rhesus Macaque Macaca mulatta XP_001107588 879 98905 S381 D K H L A I D S S N Y E Q E S
Dog Lupus familis XP_541867 872 95696 A369 C A A H S L Q A V P F E Q E S
Cat Felis silvestris
Mouse Mus musculus Q9QYS2 879 99096 S381 D K H L A I D S S N Y E Q E S
Rat Rattus norvegicus P31422 879 98942 S381 D K H L A I D S S N Y E Q E S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515487 775 87278 N310 M Q R T L C P N T T K L C D A
Chicken Gallus gallus XP_416842 879 98936 S381 D K H F T I N S S N Y E Q E S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5U9X3 867 97118 L378 A S N T V L E L M K S T N L D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91685 976 108467 K409 D S Y R L S E K V G Y E Q E S
Honey Bee Apis mellifera NP_001011624 933 103448 E411 P N L R L T S E R G Y E Q E S
Nematode Worm Caenorhab. elegans Q09630 999 113258 T447 C E D I K Q S T E G F N A D D
Sea Urchin Strong. purpuratus XP_784936 1474 165598 E952 C A E N V L D E A N H A Q E K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 25.9 99.5 68.7 N.A. 96.6 96.5 N.A. 79.1 91 N.A. 26.5 N.A. 46 48.2 39.4 33.3
Protein Similarity: 100 45.3 99.6 82.3 N.A. 98.7 98.5 N.A. 83.8 95.4 N.A. 46 N.A. 61.6 64.7 57.1 44.9
P-Site Identity: 100 20 100 26.6 N.A. 100 100 N.A. 0 80 N.A. 0 N.A. 40 33.3 0 26.6
P-Site Similarity: 100 26.6 100 53.3 N.A. 100 100 N.A. 33.3 86.6 N.A. 20 N.A. 53.3 33.3 33.3 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 16 8 0 39 0 0 8 8 0 0 8 8 0 8 % A
% Cys: 24 8 0 0 0 8 0 0 0 0 0 0 8 0 0 % C
% Asp: 47 0 8 0 0 0 39 0 0 0 0 0 0 16 16 % D
% Glu: 0 8 8 0 0 0 16 16 8 0 0 62 0 70 0 % E
% Phe: 0 0 0 8 0 0 0 0 8 0 16 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 24 0 0 0 0 0 % G
% His: 0 0 39 8 0 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 0 0 0 8 0 39 0 0 0 0 0 8 0 0 0 % I
% Lys: 0 39 0 0 8 0 0 8 0 8 8 0 0 0 8 % K
% Leu: 0 0 16 31 24 24 8 8 0 0 0 8 8 8 8 % L
% Met: 8 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 8 8 8 16 0 0 8 8 0 54 0 8 8 0 0 % N
% Pro: 8 0 0 0 0 0 8 0 0 8 0 0 0 0 0 % P
% Gln: 0 8 0 0 0 8 8 0 0 0 0 0 70 0 0 % Q
% Arg: 0 0 8 16 0 0 0 0 8 0 0 0 0 8 0 % R
% Ser: 0 16 0 0 8 8 16 47 39 0 8 0 0 0 62 % S
% Thr: 0 0 0 16 8 16 0 8 8 8 8 8 0 0 0 % T
% Val: 0 0 0 0 16 0 0 0 16 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 0 0 0 0 54 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _